RNAi is the sequence-specific mRNA degradation guided by siRNAs produced from long dsRNA by RNase Dicer. Proteins executing RNAi are present in mammalian cells but rather sustain the microRNA pathway.
Aiming for a systematic analysis of mammalian RNAi, we report here that the main bottleneck for RNAi efficiency is the production of functional siRNAs, which integrates Dicer activity, dsRNA structure, and siRNA targeting efficiency. Unexpectedly, increased expression of Dicer cofactors TARBP2 or PACT reduces RNAi but not microRNA function.
Elimination of protein kinase R, a key dsRNA sensor in the interferon response, had minimal positive effects on RNAi activity in fibroblasts. Without high Dicer activity, RNAi can still occur when the initial Dicer cleavage of the substrate yields an efficient siRNA.
9998 SCREW CAP 415/18 |
9998-18 |
CORNING |
192/pk |
EUR 103.00 |
Description: General Apparatus; Stoppers |
COVER GLASS, NO. 2, SQUARE 18 X 18MM |
2855-18 |
CORNING |
50/pk |
EUR 83.00 |
Description: Cover Glass; Cover Glass, CGW |
COVER GLASS, NO. 1, SQUARE 18 X 18MM |
2845-18 |
CORNING |
100/pk |
EUR 112.00 |
Description: Cover Glass; Cover Glass, CGW |
Bovine Serum Amyloid A (SAA) ELISA Kit |
DLR-SAA-b-48T |
DL Develop |
48T |
EUR 547.00 |
- Should the Bovine Serum Amyloid A (SAA) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
|
Description: A sandwich quantitative ELISA assay kit for detection of Bovine Serum Amyloid A (SAA) in samples from serum, plasma or other biological fluids. |
Bovine Serum Amyloid A (SAA) ELISA Kit |
DLR-SAA-b-96T |
DL Develop |
96T |
EUR 715.00 |
- Should the Bovine Serum Amyloid A (SAA) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
|
Description: A sandwich quantitative ELISA assay kit for detection of Bovine Serum Amyloid A (SAA) in samples from serum, plasma or other biological fluids. |
Human Serum Amyloid A (SAA) ELISA Kit |
DLR-SAA-Hu-48T |
DL Develop |
48T |
EUR 479.00 |
- Should the Human Serum Amyloid A (SAA) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
|
Description: A sandwich quantitative ELISA assay kit for detection of Human Serum Amyloid A (SAA) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Human Serum Amyloid A (SAA) ELISA Kit |
DLR-SAA-Hu-96T |
DL Develop |
96T |
EUR 621.00 |
- Should the Human Serum Amyloid A (SAA) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
|
Description: A sandwich quantitative ELISA assay kit for detection of Human Serum Amyloid A (SAA) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Mouse Serum Amyloid A (SAA) ELISA Kit |
DLR-SAA-Mu-48T |
DL Develop |
48T |
EUR 489.00 |
- Should the Mouse Serum Amyloid A (SAA) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
|
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Serum Amyloid A (SAA) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Mouse Serum Amyloid A (SAA) ELISA Kit |
DLR-SAA-Mu-96T |
DL Develop |
96T |
EUR 635.00 |
- Should the Mouse Serum Amyloid A (SAA) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
|
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Serum Amyloid A (SAA) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Rabbit Serum Amyloid A (SAA) ELISA Kit |
DLR-SAA-Rb-48T |
DL Develop |
48T |
EUR 508.00 |
- Should the Rabbit Serum Amyloid A (SAA) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
|
Description: A sandwich quantitative ELISA assay kit for detection of Rabbit Serum Amyloid A (SAA) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Rabbit Serum Amyloid A (SAA) ELISA Kit |
DLR-SAA-Rb-96T |
DL Develop |
96T |
EUR 661.00 |
- Should the Rabbit Serum Amyloid A (SAA) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
|
Description: A sandwich quantitative ELISA assay kit for detection of Rabbit Serum Amyloid A (SAA) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Bovine Serum Amyloid A (SAA) ELISA Kit |
RD-SAA-b-48Tests |
Reddot Biotech |
48 Tests |
EUR 555.00 |
Bovine Serum Amyloid A (SAA) ELISA Kit |
RD-SAA-b-96Tests |
Reddot Biotech |
96 Tests |
EUR 771.00 |
Human Serum Amyloid A (SAA) ELISA Kit |
RD-SAA-Hu-48Tests |
Reddot Biotech |
48 Tests |
EUR 478.00 |
Human Serum Amyloid A (SAA) ELISA Kit |
RD-SAA-Hu-96Tests |
Reddot Biotech |
96 Tests |
EUR 662.00 |
Mouse Serum Amyloid A (SAA) ELISA Kit |
RD-SAA-Mu-48Tests |
Reddot Biotech |
48 Tests |
EUR 489.00 |
Mouse Serum Amyloid A (SAA) ELISA Kit |
RD-SAA-Mu-96Tests |
Reddot Biotech |
96 Tests |
EUR 677.00 |
Rabbit Serum Amyloid A (SAA) ELISA Kit |
RD-SAA-Rb-48Tests |
Reddot Biotech |
48 Tests |
EUR 511.00 |
Rabbit Serum Amyloid A (SAA) ELISA Kit |
RD-SAA-Rb-96Tests |
Reddot Biotech |
96 Tests |
EUR 709.00 |
Bovine Serum Amyloid A (SAA) ELISA Kit |
RDR-SAA-b-48Tests |
Reddot Biotech |
48 Tests |
EUR 580.00 |
Bovine Serum Amyloid A (SAA) ELISA Kit |
RDR-SAA-b-96Tests |
Reddot Biotech |
96 Tests |
EUR 807.00 |
Human Serum Amyloid A (SAA) ELISA Kit |
RDR-SAA-Hu-48Tests |
Reddot Biotech |
48 Tests |
EUR 500.00 |
Human Serum Amyloid A (SAA) ELISA Kit |
RDR-SAA-Hu-96Tests |
Reddot Biotech |
96 Tests |
EUR 692.00 |
Mouse Serum Amyloid A (SAA) ELISA Kit |
RDR-SAA-Mu-48Tests |
Reddot Biotech |
48 Tests |
EUR 511.00 |
Mouse Serum Amyloid A (SAA) ELISA Kit |
RDR-SAA-Mu-96Tests |
Reddot Biotech |
96 Tests |
EUR 709.00 |
Rabbit Serum Amyloid A (SAA) ELISA Kit |
RDR-SAA-Rb-48Tests |
Reddot Biotech |
48 Tests |
EUR 534.00 |
Rabbit Serum Amyloid A (SAA) ELISA Kit |
RDR-SAA-Rb-96Tests |
Reddot Biotech |
96 Tests |
EUR 742.00 |
COVER GLASS, NO. 1 1/2, SQUARE 18 X 18MM |
2850-18 |
CORNING |
100/pk |
EUR 131.00 |
Description: Cover Glass; Cover Glass, CGW |
TruStrip RDT Human Serum Amyloid A (SAA) Rapid Test cards, 10 tests/pack |
SAA-RDT-10 |
Alpha Diagnostics |
1 pack |
EUR 171.00 |
TruStrip RDT Human Serum Amyloid A (SAA) Rapid Test cards, 25 tests/pack |
SAA-RDT-25 |
Alpha Diagnostics |
1 pack |
EUR 293.00 |
SAA-PEG-SAA |
abx085047-10kDa1g |
Abbexa |
10 kDa; 1 g |
EUR 453.00 |
- Shipped within 5-10 working days.
|
SAA-PEG-SAA |
abx085047-1kDa1g |
Abbexa |
1 kDa; 1 g |
EUR 453.00 |
- Shipped within 5-10 working days.
|
SAA-PEG-SAA |
abx085047-20kDa1g |
Abbexa |
20 kDa; 1 g |
EUR 453.00 |
- Shipped within 5-10 working days.
|
SAA-PEG-SAA |
abx085047-2kDa1g |
Abbexa |
2 kDa; 1 g |
EUR 453.00 |
- Shipped within 5-10 working days.
|
SAA-PEG-SAA,10K |
33-HO015015-10K |
Biochempeg |
|
|
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. |
SAA-PEG-SAA,1K |
33-HO015015-1K |
Biochempeg |
|
|
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. |
SAA-PEG-SAA,20K |
33-HO015015-20K |
Biochempeg |
|
|
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. |
SAA-PEG-SAA,2K |
33-HO015015-2K |
Biochempeg |
|
|
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. |
SAA-PEG-SAA,3.4K |
33-HO015015-3.4K |
Biochempeg |
|
|
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. |
SAA-PEG-SAA,5K |
33-HO015015-5K |
Biochempeg |
|
|
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. |
SAA |
E64C01201 |
EnoGene |
20ug |
EUR 382.00 |
FT4 (Free thyroxine) ELISA test |
18 |
Biobase |
96T/Box |
Ask for price |
- Area of application: Hormone testing
|
Description: ELISA based test for quantitative detection of FT4 (Free thyroxine) |
mPEG-SAA |
abx085023-10kDa1g |
Abbexa |
10 kDa; 1 g |
EUR 370.00 |
- Shipped within 5-10 working days.
|
mPEG-SAA |
abx085023-1kDa1g |
Abbexa |
1 kDa; 1 g |
EUR 356.00 |
- Shipped within 5-10 working days.
|
mPEG-SAA |
abx085023-20kDa1g |
Abbexa |
20 kDa; 1 g |
EUR 370.00 |
- Shipped within 5-10 working days.
|
mPEG-SAA |
abx085023-2kDa1g |
Abbexa |
2 kDa; 1 g |
EUR 356.00 |
- Shipped within 5-10 working days.
|
mPEG-SAA |
abx085023-5kDa1g |
Abbexa |
5 kDa; 1 g |
EUR 356.00 |
- Shipped within 5-10 working days.
|
SAA Protein |
abx060299-100ug |
Abbexa |
100 ug |
EUR 829.00 |
- Shipped within 5-10 working days.
|
SAA antibody |
10R-10351 |
Fitzgerald |
100 ug |
EUR 435.00 |
Description: Mouse monoclonal SAA antibody |
SAA antibody |
10-7959 |
Fitzgerald |
500 ug |
EUR 349.00 |
Description: Mouse monoclonal SAA antibody |
SAA antibody |
10-7960 |
Fitzgerald |
500 ug |
EUR 349.00 |
Description: Mouse monoclonal SAA antibody |
SAA antibody |
20-1715 |
Fitzgerald |
1 ml |
EUR 138.00 |
Description: Goat polyclonal SAA antibody |
Apo SAA antibody |
20R-1792 |
Fitzgerald |
100 ug |
EUR 673.00 |
Description: Rabbit polyclonal Apo SAA antibody |
mPEG-SAA,10K |
33-MF001015-10K |
Biochempeg |
|
|
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. |
mPEG-SAA,1K |
33-MF001015-1K |
Biochempeg |
|
|
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. |
mPEG-SAA,20K |
33-MF001015-20K |
Biochempeg |
|
|
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. |
mPEG-SAA,2K |
33-MF001015-2K |
Biochempeg |
|
|
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. |
mPEG-SAA,30K |
33-MF001015-30K |
Biochempeg |
|
|
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. |
mPEG-SAA,4K |
33-MF001015-4K |
Biochempeg |
|
|
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. |
mPEG-SAA,5K |
33-MF001015-5K |
Biochempeg |
|
|
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. |
Recombinant Human SAA |
P0209 |
FN Test |
100ug |
EUR 522.36 |
- Formulation: pH7.4, Lyophilized from a 0.2um filtered solution in PBS with 5% trehalose
- Reconstitution: Sterile distilled water
- Purity: Greater than 95% by SDS-PAGE gel analyses
- Uniprot ID: P0DJI8
|
Description: Recombinant Human protein for SAA |
Human SAA ELISA Kit |
EHS0235 |
Abclonal |
96Tests |
EUR 521.00 |
Goat SAA ELISA Kit |
EGTS0235 |
Abclonal |
96Tests |
EUR 521.00 |
Bovine SAA ELISA Kit |
EBS0235 |
Abclonal |
96Tests |
EUR 521.00 |
Chicken SAA ELISA Kit |
ECKS0235 |
Abclonal |
96Tests |
EUR 521.00 |
Anserini SAA ELISA Kit |
EAS0235 |
Abclonal |
96Tests |
EUR 521.00 |
Canine SAA ELISA Kit |
ECS0235 |
Abclonal |
96Tests |
EUR 521.00 |
Porcine SAA ELISA Kit |
EPS0235 |
Abclonal |
96Tests |
EUR 521.00 |
Rat SAA ELISA Kit |
ERS0235 |
Abclonal |
96Tests |
EUR 521.00 |
Sheep SAA ELISA Kit |
ESS0235 |
Abclonal |
96Tests |
EUR 521.00 |
Rabbit SAA ELISA Kit |
ERTS0235 |
Abclonal |
96Tests |
EUR 521.00 |
Monkey SAA ELISA Kit |
EMKS0235 |
Abclonal |
96Tests |
EUR 521.00 |
Mouse SAA ELISA Kit |
EMS0235 |
Abclonal |
96Tests |
EUR 521.00 |
4-Arm PEG-SAA |
abx085101-10kDa1g |
Abbexa |
10 kDa; 1 g |
EUR 384.00 |
- Shipped within 5-10 working days.
|
4-Arm PEG-SAA |
abx085101-10kDa5g |
Abbexa |
10 kDa; 5 g |
EUR 634.00 |
- Shipped within 5-10 working days.
|
4-Arm PEG-SAA |
abx085101-20kDa5g |
Abbexa |
20 kDa; 5 g |
EUR 634.00 |
- Shipped within 5-10 working days.
|
4-Arm PEG-SAA |
abx085101-2kDa1g |
Abbexa |
2 kDa; 1 g |
EUR 356.00 |
- Shipped within 5-10 working days.
|
8-Arm PEG-SAA |
abx085112-10kDa1g |
Abbexa |
10 kDa; 1 g |
EUR 328.00 |
- Shipped within 5-10 working days.
|
8-Arm PEG-SAA |
abx085112-10kDa5g |
Abbexa |
10 kDa; 5 g |
EUR 620.00 |
- Shipped within 5-10 working days.
|
8-Arm PEG-SAA |
abx085112-20kDa5g |
Abbexa |
20 kDa; 5 g |
EUR 620.00 |
- Shipped within 5-10 working days.
|
8-Arm PEG-SAA |
abx085112-40kDa1g |
Abbexa |
40 kDa; 1 g |
EUR 356.00 |
- Shipped within 5-10 working days.
|
4-ArmPEG-SAA,10K |
33-A44015-10K |
Biochempeg |
|
|
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. |
4-ArmPEG-SAA,20K |
33-A44015-20K |
Biochempeg |
|
|
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. |
4-ArmPEG-SAA,2K |
33-A44015-2K |
Biochempeg |
|
|
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. |
8-ArmPEG-SAA,10K |
33-A88015-10K |
Biochempeg |
|
|
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. |
8-ArmPEG-SAA,20K |
33-A88015-20K |
Biochempeg |
|
|
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. |
8-ArmPEG-SAA,40K |
33-A88015-40K |
Biochempeg |
|
|
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. |
Apo-SAA, human recombinant |
4324-10 |
Biovision |
|
EUR 137.00 |
Apo-SAA, human recombinant |
4324-1000 |
Biovision |
|
EUR 920.00 |
Apo-SAA, human recombinant |
4324-50 |
Biovision |
|
EUR 256.00 |
Apo-SAA, human recombinant |
4324-500 |
Biovision |
|
EUR 756.00 |
Human SAA ELISA Kit |
DEIA450 |
Creative Diagnostics |
96T |
EUR 1060.00 |
Description: ThisHuman SAA ELISA Kit is to be used for the in vitro quantitative determinationof human serum amyloid A (SAA) concentrations in serum, plasma, cell culture supernatant, and other biological fluids. |
AlbuSorb™ Kit |
A185-18 |
Biotech Support Group |
18 grams AlbuSorb™ Bead & Buffer (360 preps, 25 µl serum) |
Ask for price |
Description: Albumin Removal Kit |
Encephalitozoon cuniculi whole cell antigen suspension |
18-2002 |
Medicago |
1 ml |
EUR 365.00 |
Anti-Trimethyl-Histone H3 (Lys27) Rabbit Monoclonal Antibody, Clone#RM175 |
M06819-18 |
BosterBio |
100ug |
EUR 479.00 |
Description: Anti-Trimethyl-Histone H3 (Lys27) Rabbit Monoclonal Antibody, Clone#RM175 tested in WB, ELISA, Multiplex, IHC, reactive to All Vertebrates |
IL-7, Interleukin-7, human |
RC212-18 |
BBI Biotech |
2ug |
EUR 104.38 |
- Product category: Proteins/Recombinant Proteins/Cytokines
|
TSLP, Thymic Stromal Lymphopoietin, human |
RC213-18 |
BBI Biotech |
2ug |
EUR 104.38 |
- Product category: Proteins/Recombinant Proteins/Cytokines
|
LIF, Leukemia inhibitory factor, human |
RC214-18 |
BBI Biotech |
2ug |
EUR 101.33 |
- Product category: Proteins/Recombinant Proteins/Cytokines
|
FGF-7, KGF-1, Fibroblast Growth Factor-7, human |
RC215-18 |
BBI Biotech |
2ug |
EUR 104.38 |
- Product category: Proteins/Recombinant Proteins/Cytokines
|
Epiregulin, human |
RC216-18 |
BBI Biotech |
5ug |
EUR 104.38 |
- Product category: Proteins/Recombinant Proteins/Growth Factors
|
IFN lambda 1 (IL-29), human |
RC217-18 |
BBI Biotech |
5ug |
EUR 104.38 |
- Product category: Proteins/Recombinant Proteins/Cytokines
|
GMF beta, Glia Maturation Factor beta, human |
RC218-18 |
BBI Biotech |
2ug |
EUR 104.38 |
- Product category: Proteins/Recombinant Proteins/Cytokines
|
Efficient mammalian RNAi may use substrates with some features of microRNA precursors, merging both pathways even more than previously suggested. Although optimized endogenous Dicer substrates mimicking miRNA features could evolve for endogenous regulations, the same principles would make antiviral RNAi inefficient as viruses would adapt to avoid efficacy.